Figure 1.

SARS-CoV-2 NP- and S-RBD-Specific Antibodies in COVID-19 Convalescent Individuals

(A) Titration of individual serum samples.

(B) Serological responses of 14 COVID-19 patients to recombinant NP (top) and S-RBD (bottom). Dilution of 1:50 was used for IgM and 1:450 for IgG.

(C) Data from the same experiments with (A) were presented as AUC.

(D) IgG isotypes of 14 COVID-19 patients to recombinant NP and S-RBD.

NP, nucleocapsid protein; S-RBD, receptor binding domain of spike protein; HD, healthy donor; Pt, patient; AUC, area under curve. The experiment was performed in duplicates. Date are presented as mean ± SEM. For HD 1–3, the sera were collected in 2018. For HD 4–6, the sera were from close contacts and collected in 2020. ^∗p < 0.05, 0.05 < ^∗∗p < 0.001, ^∗∗∗p < 0.001.