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. 2020 May 3;52(6):971–977.e3. doi: 10.1016/j.immuni.2020.04.023

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© 2020 Elsevier Inc.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Measurement of Neutralizing Antibody Titers in COVID-19 Convalescent Individuals

(A) Correlation analysis of neutralizing antibody titers in COV1D-19 patients measured by pseudovirus and live SARS-CoV-2 (n = 20).

(B) Neutralizing curves of 14 COVID-19 patients measured by pseudovirus-based assay. The experiment with patients was performed in triplicates. The experiment with healthy donors was performed in duplicates.

(C) Measurement of neutralizing antibody titers of 14 COVID-19 patients by pseudovirus-based assay.

(D) Correlation between NAT50 and AUC of anti-S-RBD (left) and anti-NP (right) IgG (n = 14).

HD, healthy donor; Pt, patient; AUC, area under curve; NAT50, neutralizing antibody titers. Date are presented as mean ± SEM. ^∗p < 0.05, 0.05 < ^∗∗p < 0.001, ^∗∗∗p < 0.001.