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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Psychosom Med. 2020 May;82(4):366–376. doi: 10.1097/PSY.0000000000000799

Table 2.

Sibling Chronic Illness and Somatic Symptoms

Source Study Design Sample Country and N Age Range/Mean (SD) Sibling Disease Somatic Symptom Measurement Results
Cadman (1988) Cross-sectional Canada 3,294 12–16 Blindness, deafness, severe speech problems, severe pain, asthma, heart problems, epilepsy, kidney disease, arthritis, cerebral palsy, muscular dystrophy, spina bifida, diabetes, cancer, cystic fibrosis, physical deformities Survey Diagnostic Instrument Children with sibling with chronic health problems only at small risk of somatization (OR = 1.6)
Gold (1999) Cross-sectional United States 97- siblings 56- ill children Siblings 11.24 Ill children 10.41 Sickle cell disease CBCL Report less somatization than ill siblings. Do not have clinically significant levels of somatization when compared to sex matched norms for CBCL
Hamama (2008) Cross-sectional Israeli Jewish 100 Siblings 8–19 Cancer Frequent symptoms scale Role overload correlated with somatic symptoms in siblings; somatic symptoms negatively correlated with self-control and self-efficacy
Lahteenmaki (2004) Cross-sectional/repeated measures Finland 33 siblings 357 healthy controls 3–17 Cancer Huttunen’s test No difference between siblings and controls on somatic symptoms
Massie (2012) Cross-sectional Canadian 108 7–17 Cancer CBCL Siblings reported higher somatic problems than normative population
Von Dongen-Melman (1995) Cross-sectional Netherlands 60 4–16 Cancer Amsterdam Biographic Questionnaire for Children (ABV-K); CBCL On the ABV-K, siblings reported significantly less somatization than controls. No difference found on CBCL somatization subscale.
Zeltzer (1996) Cross-sectional United States 254 5–18 (10.65) Cancer National Health Survey Data; CBCL; Youth Self Report Parent-reported and sibling self-reported higher somatization than non-clinical norms, but lower than clinical normative samples. Adolescent boys had somatization scores as high as clinical normative scores. Higher sibling somatization associated with higher sibling reported interpersonal adjustment difficulties.