Table 2:
Factors associated with Hair Cortisol Concentrations (HCC) in Bivariable Regression Analyses
| CV1 (n=396) | CV2 (n=347) | CV3 (n=252) | CV4 (n=63) | |||||
|---|---|---|---|---|---|---|---|---|
| Variable | Estimate (95% CI) | P-value | Estimate (95% CI) | P-value | Estimate (95% CI) | P-value | Estimate (95% CI) | P-value |
| Black Race (ref: White/Other) | 1.08 (0.81, 1.35) | <0.0001 | 1.36 (1.03, 1.68) | <0.0001 | 1.45 (1.07, 1.82) | <0.0001 | 1.69 (0.66, 2.71) | 0.0013 |
| Mother’s age at M1 | −0.03 (−0.05, 0.00) | 0.043 | ||||||
| Mother’s education at M1 (ref: <high school): | 0.014 | 0.0039 | 0.0678 | |||||
| High School/GED | −0.06 (−0.66, 0.54) | −0.63 (−1.77, 0.5) | −0.82 (−1.78, 0.13) | |||||
| Technical School | −0.15 (−0.88, 0.58) | −0.56 (−1.87, 0.75) | −0.83 (−2.07, 0.41) | |||||
| College Degree | −0.58 (−1.2, 0.04) | −1.13 (−2.26, 0) | −1.27 (−2.23, −0.31) | |||||
| Grad/Professional | −0.58 (−1.24, 0.07) | −1.4 (−2.57, −0.24) | −1.21 (−2.2, −0.23) | |||||
| Marital status at M1 (ref: never married) | 0.0014 | <0.0001 | 0.0002 | |||||
| Divorced | −0.43 (−1.86, 1.01) | 1.13 (−0.4, 2.67) | −0.08 (−1.73, 1.56) | |||||
| Separated | −0.1 (−1.2, 0.99)− | −0.52 (−1.63, 0.59) | −1.22 (−2.87, 0.43) | |||||
| Living with partner | −0.45 (−0.87, −0.03) | −0.3 (−0.96, 0.36) | −0.4 (−1.17, 0.37) | |||||
| Married | −0.71 (−1.04, −0.37) | −1.1 (−1.5, −0.7) | −1.13 (−1.62, −0.63) | |||||
| Mother’s health Insurance: private (ref: public ins.) | −0.6 (−0.89, −0.32 | <0.0001 | −1.04 (−1.4, −0.69) | <0.0001 | −0.73 (−1.17, −0.3) | 0.0009 | −1.07 (−2.23, 0.08) | 0.068 |
| Income at M1 (ref: <$25K per year) | 0.0019 | 0.0031 | 0.002 | |||||
| $25K-$65K | −0.19 (−0.54, 0.16) | −0.64 (−1.07, −0.22) | −0.49 (−1.05, 0.07) | 0.40 (−1.17, 1.98) | ||||
| >$65K | −0.64 (−0.99, −0.28) | −1.15 (−1.56, −0.73) | −0.93 (−1.46, −0.39) | −1.46 (−2.9, −0.03) | ||||
| Household structure (ref: single parent, 5+ people in the home) | 0.0018 | <0.0001 | 0.0004 | |||||
| Single parent, 2–4 | −0.12 (−0.67, 0.43) | −0.61 (−1.28, 0.06) | −0.36 (−1.07, 0.35) | |||||
| Both parents, 5+ | −0.62 (−1.13, −0.1) | −1.36 (−1.99, −0.74) | −1.18 (−1.86, −0.5) | |||||
| Both parents, 2–4 | −0.74 (−1.2, −0.28) | −1.33 (−1.91, −0.75) | −1.08 (−1.71, −0.45) | |||||
| Mother’s weight at M1 (Kg) | 0.01 (0.00, 0.02) | 0.004 | ||||||
| Mother’s BMI at Ml (kg/m2) | 0.03 (0.01, 0.05) | 0.0052 | ||||||
| KIDI total score (M2) | −2.24 (−3.27, −1.21) | <0.0001 | ||||||
| CAPI Rigidity Score | 0.02 (0.01, 0.03) | 0.0001 | 0.03 (0.02, 0.04) | <0.0001 | 0.03 (0.00, 0.05) | 0.0002 | ||
| CAPI Abuse Score | 0 (0, 0.01) | 0.0031 | ||||||
| Irritable temperament (TEMPS-A) | −2.93 (−6.25, 0.39) | 0.0837 | ||||||
| Maternal depression (CESD) | 0.08 (0.01, 0.15) | 0.0166 | ||||||
| Gestational age (weeks) | −0.13 (−0.23, −0.03) | 0.0134 | ||||||
| Birthweight (kg) | −0.25 (−0.53, 0.03) | 0.08 | ||||||
| Female sex (ref: male) | −0.37 (−0.66, −0.08) | 0.0117 | 0.33 (−0.01, 0.67) | 0.0601 | ||||
| BITSEA Problem Total | 0.04 (0.01, 0.06) | 0.0087 | 0.04 (0.01, 0.06) | 0.0036 | ||||
| LN Cortisol at CVl | 0.40 (0.19, 0.62) | 0.0002 | 1.1 (0.25, 1.96) | 0.0115 | ||||
| LN Cortisol at CV2 | 0.28 (0.09, 0.46) | 0.0034 | 0.69 (0.26, 1.11) | 0.0016 | ||||
| Child care at organized daycare | −1.41 (−2.9, 0.07) | 0.0624 | ||||||
| Bracken School Readiness Competency | −0.03 (−0.07, 0.00) | 0.0624 | ||||||
| SAI (ref: l=worst) | 0.0001 | <0.0001 | 0.0007 | 0.0006 | ||||
| 2 | −0.09 (−0.63, 0.46) | −0.07 (−0.69, 0.55) | −0.06 (−0.76, 0.65) | 2.27 (0.17, 4.37) | ||||
| 3 | −0.17 (−0.66, 0.32) | −0.92 (−1.55, −0.3) | −0.65 (−1.38, 0.09) | 1.73 (−0.25, 3.71) | ||||
| 4 | −0.52 (−0.96, −0.09) | −1.31 (−1.86, −0.76) | −0.79 (−1.45, −0.14) | 1.39 (−0.44, 3.21) | ||||
| 5 | −0.9 (−1.34, −0.46) | −1.53 (−2.06, −0.99) | −1.12 (-1.73, −0.51) | −0.29 (−1.96, 1.38) | ||||
Note: Only bivariable relationships with p<0.1 are listed. *HCC: Hair Cortisol Concentrations, TEMPS-A: Temperament Evaluation of Memphis, Pisa, Paris & San Diego-Auto, CESD: Center for Epidemiological Studies Depression Scale, HV: Home Visit in CANDLE, BITSEA: Brief Infant-Toddler Social-Emotional Assessment scale, CAPI: Child Abuse Potential Index, KIDI: Knowledge of Infant Development Index, SAI: Socioeconomic Adversity Index.