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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2020 Feb 17;29(5):936–941. doi: 10.1158/1055-9965.EPI-19-1504

Table 2.

Sensitivity, specificity, and positive predictive value (PPV) of treatment (chemotherapy, surgery, radiotherapy, bone marrow transplant (BMT)) data abstracted from cancer registry (California Surveillance Program), OHSPD/hospitalization discharge, and SEER-Medicare data, compared to treatment abstracted from medical records among B-cell NHL cases diagnosed in Los Angeles County (2004–08).

Overall DLBCL FL CLL/SLL
Treatment CSP N=695 OSHPD N=665 Medicare N=401 Combined N=698 CSP N=243 OSHPD N=235 Medicare N=133 Combined N=243 CSP N=167 OSHPD N=162 Medicare N=97 Combined N=167 CSP N=105 OSHPD N=98 Medicare N=70 Combined N=105
Chemotherapy
 Sensitivity (%) 74 65 80 92 88 67 76 97 65 59 70 90 34 57 94 81
 Specificity (%) 99 72 51 56 67 100 * 67 100 68 90 70 100 86 52 63
 PPV (%) 100 94 91 93 100 100 100 100 100 92 98 95 100 91 80 83
Surgery
 Sensitivity (%) 73 22 52 83 84 41 63 83 76 10 52 81 31 12 50 54
 Specificity (%) 76 90 74 61 75 84 63 61 45 89 77 36 92 99 87 86
 PPV (%) 68 60 61 60 63 58 49 51 67 56 80 65 57 75 62 56
Radiotherapy
 Sensitivity (%) 67 11 41 77 61 12 32 71 61 3 40 75 50 * 100 100
 Specificity (%) 99 97 89 91 100 96 86 89 99 98 87 92 99 * 93 96
 PPV (%) 95 57 49 75 100 62 47 77 96 33 46 75 50 * 25 33
BMT
 Sensitivity (%) 42 98 87 98 25 96 88 96 * * * * * * * *
 Specificity (%) 100 98 98 98 100 98 99 98 * * * * * * * *
 PPV (%) 100 87 72 83 100 85 88 85 * * * * * * * *
*

insufficient number of cases receiving treatment to calculate

CLL/SLL: Chronic lymphocytic leukemia/small lymphocytic lymphoma. DLBCL: Diffuse large B-cell lymphoma. FL: Follicular lymphoma.