Table 2.
Sensitivity, specificity, and positive predictive value (PPV) of treatment (chemotherapy, surgery, radiotherapy, bone marrow transplant (BMT)) data abstracted from cancer registry (California Surveillance Program), OHSPD/hospitalization discharge, and SEER-Medicare data, compared to treatment abstracted from medical records among B-cell NHL cases diagnosed in Los Angeles County (2004–08).
| Overall | DLBCL | FL | CLL/SLL | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Treatment | CSP N=695 | OSHPD N=665 | Medicare N=401 | Combined N=698 | CSP N=243 | OSHPD N=235 | Medicare N=133 | Combined N=243 | CSP N=167 | OSHPD N=162 | Medicare N=97 | Combined N=167 | CSP N=105 | OSHPD N=98 | Medicare N=70 | Combined N=105 |
| Chemotherapy | ||||||||||||||||
| Sensitivity (%) | 74 | 65 | 80 | 92 | 88 | 67 | 76 | 97 | 65 | 59 | 70 | 90 | 34 | 57 | 94 | 81 |
| Specificity (%) | 99 | 72 | 51 | 56 | 67 | 100 | * | 67 | 100 | 68 | 90 | 70 | 100 | 86 | 52 | 63 |
| PPV (%) | 100 | 94 | 91 | 93 | 100 | 100 | 100 | 100 | 100 | 92 | 98 | 95 | 100 | 91 | 80 | 83 |
| Surgery | ||||||||||||||||
| Sensitivity (%) | 73 | 22 | 52 | 83 | 84 | 41 | 63 | 83 | 76 | 10 | 52 | 81 | 31 | 12 | 50 | 54 |
| Specificity (%) | 76 | 90 | 74 | 61 | 75 | 84 | 63 | 61 | 45 | 89 | 77 | 36 | 92 | 99 | 87 | 86 |
| PPV (%) | 68 | 60 | 61 | 60 | 63 | 58 | 49 | 51 | 67 | 56 | 80 | 65 | 57 | 75 | 62 | 56 |
| Radiotherapy | ||||||||||||||||
| Sensitivity (%) | 67 | 11 | 41 | 77 | 61 | 12 | 32 | 71 | 61 | 3 | 40 | 75 | 50 | * | 100 | 100 |
| Specificity (%) | 99 | 97 | 89 | 91 | 100 | 96 | 86 | 89 | 99 | 98 | 87 | 92 | 99 | * | 93 | 96 |
| PPV (%) | 95 | 57 | 49 | 75 | 100 | 62 | 47 | 77 | 96 | 33 | 46 | 75 | 50 | * | 25 | 33 |
| BMT | ||||||||||||||||
| Sensitivity (%) | 42 | 98 | 87 | 98 | 25 | 96 | 88 | 96 | * | * | * | * | * | * | * | * |
| Specificity (%) | 100 | 98 | 98 | 98 | 100 | 98 | 99 | 98 | * | * | * | * | * | * | * | * |
| PPV (%) | 100 | 87 | 72 | 83 | 100 | 85 | 88 | 85 | * | * | * | * | * | * | * | * |
insufficient number of cases receiving treatment to calculate
CLL/SLL: Chronic lymphocytic leukemia/small lymphocytic lymphoma. DLBCL: Diffuse large B-cell lymphoma. FL: Follicular lymphoma.