Table 1.
Outcomes and Baseline Characteristics Among Patients With COVID-19 Stratified Into Those With Preexisting Liver Disease and Without Liver Disease
Before propensity matching |
After propensity matching |
|||||
---|---|---|---|---|---|---|
COVID-19 with liver disease (n = 250) | COVID-19 without liver disease (n = 2530) | RR, RD, or P value | COVID-19 with liver disease (n = 250) | COVID-19 without liver disease (n = 250) | RR, RD, or P value | |
Outcomes | ||||||
Mortality, %, (n/total) | 12.0 (30/250) | 4.3 (110/2530) | RR: 2.8 (1.9, 4.0) RD: 7.7% (3.5%, 11.75%) P < .001 |
12.0 (30/250) | 4.0 (10/250) | RR: 3.0 (1.5, 6.0) RD: 8.0% (3.3%, 12.7%) P = .001 |
Hospitalization rate | 52.0 (130/250) | 30.0 (760/2530) | RR: 1.7 (1.2, 2.0) RD: 22.0% (15.5%, 28.4%) P < .001 |
48.0 (120/250) | 36.0 (90/250) | RR: 1.3 (1.1, 1.6) RD: 12.0% (3.4%, 20.6%) P = .006 |
Characteristics | ||||||
Age, y, mean ± SD | 55.2 ± 14.6 | 51.6 ± 17.8 | <.01 | 55.4 ± 14.4 | 56.7 ± 15.3 | .36 |
Female, n (%) | 140 (56) | 1570 (62) | .06 | 140 (56) | 140 (56) | 1.00 |
Race: white, n (%) | 130 (52) | 1220 (48.2) | .25 | 130 (52) | 130 (52) | 1.00 |
Nicotine dependence, n (%) | 60 (24) | 190 (7.5) | <.01 | 50 (20) | 50 (20) | 1.00 |
Body mass index >30.0 to 30.9 kg/m2, n (%) | 60 (24) | 310 (12.5) | <.01 | 50 (20) | 50 (20) | 1.00 |
Race: black or African American, n (%) | 100 (40) | 1000 (39.5) | .88 | 100 (40) | 110 (44) | .36 |
Hypertension, n (%) | 170 (68) | 1020 (40.3) | <.01 | 170 (68) | 170 (68) | 1.00 |
Diabetes mellitus, n (%) | 120 (48) | 520 (14.8) | <.01 | 110 (44) | 110 (44) | 1.00 |
Chronic lower respiratory diseases, n (%) | 100 (40) | 280 (11.0) | <.01 | 100 (40) | 70 (28) | .01 |
Chronic kidney disease, n (%) | 80 (32) | 305 (7.2) | <.01 | 80 (32) | 50 (20) | .01 |
Heart failure, n (%) | 60 (24) | 220 (8.7) | <.01 | 60 (24) | 50 (20) | .28 |
NOTE. Outcomes and baseline characteristics are compared before and after propensity score matching of groups.
RD, risk difference; RR, risk ratio; SD, standard deviation.