Fig. 5.

Key interactions obtained from (A) the initial complex structure of TLR3 and vaccine complex, (B) the stabilized TLR3 vaccine complex obtained from MD simulation. TLR3 receptor is shown in green color, and the vaccine is shown in cyan color in both panels. van der Waals interactions, proximal interactions, polar contacts, hydrogen bonds, aromatic contacts, hydrophobic contacts, carbonyl interactions, and amide-amide interactions are shown in yellow, grey, red, white dashed, white long-dashed, green dashed, black-white dashed and in blue dashed lines respectively.