Fig. 2.

Heat map representation of RT-qPCR validation of genes involved in cell cycle and ubiquitination process under the influence of exogenous treatments. The heat map was reported as the Z score, which is the scaled as gene expression measurement (blue = − 3 to red = 3).The time interval adopted for sample collection were listed as T1-0th h, T2-12th h, T3-24th h, T4-36th h, T5-48th h and T6-72nd h. Where the list of genes considered for analysis includes H2A-histone H2A (NCBI Acc. No. HM003232), H2B-histone H2B (NCBI Acc. No. GW696866), H3-histone H3 (NCBI Acc. No. HM003305), H4-histone H4 (NCBI Acc. No. HM003230), CYCB2-cyclin B (NCBI Acc. No. JF795471), CYCD1- cyclin-D1 (NCBI Acc. No. X83369), CYCD3- cyclin D3 (NCBI Acc. No. AB247282), CDKA1- cyclin dependent kinase A (NCBI Acc. No. AB247281), UBI40Srib-ubiquitin-40S ribosomal protein S27 (NCBI Acc. No. HM003234), UBICE-ubiquitin-conjugating enzyme E2 variant 1D (NCBI Acc. No. HM003308), UBI40Srib27-ubiquitin-40S ribosomal protein S27 protein (NCBI Acc. No. HM003307), Cyclophilin (NCBI Acc. No. HM003242), E2F-elongation factor 2 (NCBI Acc. No. JK341471) and Tubulin-tubulin alpha-3 (NCBI Acc. No. DQ444294) (color figure online)