Fig. 5.

Silencing of ERAP1 increases the length of Ala2 and non-Pro/Ala2 peptides but not Pro2 peptides. Frequencies of peptides in different lengths were compared between ERAP1-competent and -silenced HeLa.ABC-KO.B51 cells within three subpeptidomes: Pro2 (A), Ala2 (B), and non-Pro/Ala2 (C) peptides. Two independent experiments were carried out. Chi-squared test with Bonferroni correction used for statistics. Dashed box highlights the data with significant differences between ERAP1-competent and -silenced cells.