Figure 4.

Palmitoylation of barttin is decreased in the kidneys of Zdhhc7^−/− mice (ABE). A and B, kidney tissues isolated from the newborn (P0) and adult (P90) Zdhhc7^+/+ (WT) (n = 3) and Zdhhc7^−/− (KO) (n = 3) mice were collected for ABE analysis. Representative Western blots are shown in A following by quantification (B). *, p < 0.05; **, p < 0.01, Student's t test. Bars, means + S.D. (error bars). C, representative silver staining demonstrating a global protein palmitoylation in mouse kidneys from newborn (P0) and adult (P90) Zdhhc7^+/+ and Zdhhc7^−/− mice.