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. 2020 Mar 19;295(18):5995–6006. doi: 10.1074/jbc.RA120.012791

Table 4.

Kinetic data of humanized anti-ROR2 mAbs

Clone namea Heavy and light chains Human identity (%) KD (nm) kon (104 m−1 s−1) koff (10−3 s−1) χ2
hX3.12.5 VH1,VL2 87 2.6 19 0.48 0.48
hX3.12.6 VH2,VL2 87 3.8 6.0 0.22 1.6
hX3.12.7 VH3,VL2 80b 1.4 11 0.16 2.7
hX3.12.8 VH4,VL2 84b 5.2 13 0.67 0.70
h401.6 VH2,VL2 87 16 1.4 0.23 0.09

a Clone names have been shortened for simplicity to exclude “XBR2-401” from the front.

b Closest reference gene on IMGT/DomainGapAlign is not human.