Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 29;14:1609–1620. doi: 10.2147/DDDT.S243383

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Li et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

ANI inhibited NLRP3 inflammasome activation. The mice were randomly divided into four groups (n = 5): Control group, ANI-200 group, ANI-200+pcDNA-NLRP3 group and ANI-200+EV group. (A) The mRNA level of ASC was measured by RT-qPCR. (B) The protein level of ASC was measured by Western blotting. (C) The mRNA level of caspase 1 was measured by RT-qPCR. (D) The protein level of caspase 1 was measured by Western blotting. (E) The mRNA level of IL-18 was measured by RT-qPCR. (F) The protein level of IL-18 was measured by Western blotting. (G) The mRNA level of IL-1β was measured by RT-qPCR. (H) The protein level of IL-1β was measured by Western blotting. (*p < 0.05 vs control group, #p < 0.05 vs ANI-200 group, &p < 0.05 vs ANI-200+pcDNA-NLRP3 group).