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. 2012 Oct 17;2012(10):CD004398. doi: 10.1002/14651858.CD004398.pub3

2. Characteristics of the included interventions: message.

Study (PEM) Clinical area Type of targeted behaviour* Purpose¥ Level of evidence Educational component
Austin 2003 (HERS trial report) Oestrogen replacement therapy for menopausal women 1 5 6 4
Austin 2004‐A (WHI trial report) Oestrogen replacement therapy for menopausal women 1 5 6 4
Austin 2004‐B (ALLHAT trial report) Hypertension 1 6 6 4
Austin 2005 Cardiovascular disease 1 6 6 4
Avorn 1983 No specific clinical area 1; 2 6 4 3
Azocar 2003 Depression 1; 3; 4; 5 6 4 3
Barbaglia 2009 (WHI trial report) Oestrogen replacement therapy for menopausal women 1 5 6 4
Bearcroft 1994 Chest radiography 5; 6; 7 5 4 4
Beaulieu 2004 Stable angina 1 6 4 3
Bjornson 1990 Cardiovascular disease 1 6 6 4
Black 2002 (EHC‐OM bulletin) Glue ear surgery 5; 8 5 2 4
Buyle 2010 Antibiotic treatment 1; 2 6 4 4
Coopersmith 2002 Central venous catheter insertion 3 6 9 3
Denig 1990 Antispasmodic drugs for Irritable bowel syndrome and renal colic spasms 1 6 9 4
Dormuth 2004 No specific clinical area 1 6 2 4
Fijn 2000 Antithrombotic therapy  1 3 4 4
Fonarow 2009 (MIRACL trial report) Cardiovascular disease 1 3 6 4
Fonarow 2009 (PROVE‐IT TIMI 22 trial report) Cardiovascular disease 1 3 6 4
Fonarow 2009 (ACC‐AHA‐STEMI guidelines) Cardiovascular disease 1; 3; 4; 5; 6; 7; 8; 9; 10; 11; 15 6 4 4
Fonarow 2009 (AHA‐AHA‐NS guidelines) Cardiovascular disease 1; 3; 4; 5; 6; 7; 8; 9; 10; 11; 15 6 4 4
Fukuda 2009 Breast‐conserving surgery 1; 8 3 4 4
Guay 2007 (WHI publication) Oestrogen replacement therapy for menopausal women 1 5 6 4
Haas 2004 (HERS publication) Oestrogen replacement therapy for menopausal women 1 5 6 4
Haas 2004 (WHI publication) Oestrogen replacement therapy for menopausal women 1 5 6 4
Hersh 2004 (WHI; HERS; HERSIII publications) Oestrogen replacement therapy for menopausal women 1 5 6 4
Jackevicius 2001 Cardiovascular disease 1 3 6 4
Jameson 2010 Orthopaedic surgery 1 3 4 4
Jousimaa 2002 Unclear 16 3 4 4
Juurlink 2004 Cardiovascular disease 1 3 6 4
Kabir 2007 (LIFE publication) Hypertension 1 6 6 4
Kabir 2007 (ALLHAT publication) Hypertension 1 6 6 4
Kabir 2007 (VALUE trial report) Hypertension 1 6 6 4
Kajita 2012 Osteoporosis prevention 3; 9; 10 6 9 4
Kottke 1989 Smoking cessation 9 3 9 4
Lam 2009 Diabetes 1 5 6 4
Majumdar 2003 (HOPE trial report) Cardiovascular disease 1 3 6 4
Majumdar 2003 (RALES trial report) Cardiovascular disease 1 3 6 4
Majumdar 2004 (WHI trial report) Oestrogen replacement therapy for menopausal women 1 5 6 4
Mason 1998 Depression 1 3 2 4
Mason 2001 (EHC‐OM bulletin) Glue ear surgery 5; 8 5 2 4
Matowe 2002 X‐rays examination 7 6 4 4
Meyer 2007 Pneumonia 1 5 4 4
Oakeshott 1994 X‐rays examination 6; 7 6 4 4
Perria 2007 Diabetes 3 6 4 4
Roberts 2007 Protheses 3 6 4 4
Santerre 1996 Caesarean section 5 5 4 4
Shah 2008 Diabetes 1 4 3 4
Stafford 2004 (ALLHAT trial report) Hypertension 1 3 6 4
Tsuji  2009 Depression 1; 4 3 4 3
Wang 2005 (ADA guidelines; ATP III trial report) Diabetes 3; 12 3 4 4
Watson 2001 Inflammation 1 3 4 4
Weiss 2011 Antibiotic treatment 1 5 8 3

* Type of targeted behaviour: 1 = prescribing/treatment; 2 = financial (resource use); 3 = general management of a problem; 4 = diagnosis; 5 = procedures; 6 = referrals; 7 = test ordering; 8 = surgery; 9 = patient education/advice; 10 = clinical prevention service; 11 = screening; 12 = reporting; 13 = professional‐patient communication; 14 = record keeping; 15 = discharge planning; 16 = unclear.

Purpose: 1 = initiation of management (e.g. introduction of new technology); 2 = stopping introduction of new management; 3 = increase of established management; 4 = cessation of established management; 5 = reduction of established management; 6 = modification of management (e.g. increased management in one activity, reduction in another).

Level of evidence: 1 = system (computerised decision support services); 2 = summary (evidence‐based textbooks); 3 = systematic review of RCTs; 4 = clinical practice guidelines developed through formal consensus process; 5 = other synthesis; 6 = original RCT; 7 = original study not RCT; 8 = expert opinion; 9 = unclear.

Educational component: 1 = continuing professional development (CPD) credits to recipients of PEMs; 2 = PEM delivered within a formal education programme; 3 = clear statement in in the study that the PEM is intended for education; 4 = no clear educational component.

Tailoring: 1 = tailored to individuals based on diagnostic, behavioural, or motivational characteristics; 2 = tailored to groups of individuals; 3 = personalised, but not tailored (person's name on the information); 4 = generic; 5 = unclear.