Table 2.
Significant ANOVA group effects
| Region | Side | MNI coordinates | Z-max | Cluster size (mm3) |
|---|---|---|---|---|
| Own body (0% morph) condition: cisgender > transgender | ||||
| Cerebellum | R | (4, −72, −22) | 3.28 | 1463 |
| Postcentral gyrus | L | (−46, −28, 58) | 3.75 | 1462 |
| Superior parietal lobule | L | (−34, −50, 62) | 3.72 | |
| Bodies same as birth-assigned sex (+80% and +100% morph) condition: cisgender > transgender | ||||
| Postcentral gyrus | L | (−48, −30, 48) | 3.76 | 2429 |
| Superior parietal lobule | L | (−38, −52, 62) | 3.50 | |
| Supramarginal gyrus | L | (−50, −38, 46) | 3.47 | |
| Left thalamus | L | (−10, −16, 6) | 3.59 | 837 |
| Right thalamus | R | (14, −10, 12) | 3.39 | |
| Cerebellum | R | (28, −52, −26) | 3.20 | 655 |
| Superior lateral occipital cortex | R | (32, −66, 44) | 3.27 | 578 |
| dACC and paracingulate | L | (−6, 28, 36) | 3.29 | 526 |
| Bodies opposite to birth-assigned sex (−80% and −100% morph) condition: transgender > cisgender | ||||
| dACC and paracingulate | R | (10, 30, 24) | 3.84 | 1141 |
| Androgynous body (−40% and −60% morph) condition: transgender > cisgender | ||||
| pACC and paracingulate | L | (−4, 40, −2) | 3.53 | 882 |
| Parametric analysis (regions correlated to greater “me” rating when viewing morphs opposite to birth-assigned sex [−20% to −100% Morph]): transgender > cisgender | ||||
| Posterior cingulate gyrus | (0, −36, 46) | 3.76 | 8350 | |
| Posterior parahippocampus and hippocampus | L | (−24, −40, −12) | 3.64 | |
| Lateral occipital cortex | L | (−48, −68, 14) | 3.62 | |
| Temporal occipital fusiform cortex | L | (−26, −48, −12) | 3.57 | |
| Precuneous cortex | R | (2, −40, 56) | 3.53 | |
| Superior lateral occipital cortex | R | (58, −60, 20) | 3.41 | 1257 |
| Inferior lateral occipital cortex | R | (42, −64, 6) | 3.14 | |
| Frontal pole | L | (−18, 72, 4) | 3.26 | 843 |
| Frontal pole | R | (6, 58, −10) | 3.23 | |
| pACC | L | (−2, 44, 2) | 3.19 | |
| Frontal medial cortex | L | (−4, 54, −10) | 3.16 | |
| PPI analysis (regions functionally connected to pACC region of interest during the androgynous body [−40% and −60% morph] condition): transgender > cisgender | ||||
| Occipital pole | R | (24, −96, 2) | 3.46 | 1205 |
| Inferior lateral occipital cortex | R | (42, −76, −4) | 3.10 | |
| Occipital fusiform gyrus | R | (28, −82, −8) | 3.03 | |
| Lingual gyrus | R | (2, −72, −12) | 3.22 | 725 |
| Occipital pole | L | (−28, −96, 0) | 3.18 | |
| Occipital fusiform gyrus | L | (−18, −84, −14) | 3.05 | |
All findings were in the long 2 s viewing condition. All contrasts except the parametric analysis are in contrast with the scrambled image baseline