Table 3.

Summary of ANCOVA results for ROI analysis demonstrating differences in cortical ODI, with and without controlling for cortical thickness

	MCI vs. control				AD vs. control
	ODI (uncorrected)		ODI (corrected for CT)		ODI (uncorrected)		ODI (corrected for CT)
ROI	β	P FDR	β	P FDR	β	P FDR	β	P FDR
Frontal	−5.2E − 3	0.502	−3.2E − 3	0.758	−2.8E − 2	2.0E − 6	−1.8E − 2	3.6E − 3
Temporal	−5.3E − 3	0.502	−2.6E − 3	0.758	−2.4E − 2	4.4E − 6	−1.6E − 2	3.6E − 3
Parietal	−8.4E − 3	0.421	−6.2E−3	0.698	−3.8E−2	1.4E − 7	−2.6E − 2	3.0E − 4
Precuneus	−1.8E − 3	0.857	−6.4E − 4	0.992	−2.6E − 2	3.8E − 5	−1.8E − 2	3.6E−3
Ant. cingulate	−3.1E−5	0.995	−5.5E − 5	0.992	−1.9E − 2	1.1E − 3	−1.9E − 2	2.3E−3
Post. cingulate	−3.1E − 3	0.736	−2.9E − 3	0.758	−1.9E − 2	1.1E − 3	−1.5E − 2	8.3E − 3
Entorhinal	−1.8E − 2	0.421	−1.4E−2	0.500	−2.8E − 2	4.9E − 3	2.1E − 2	0.052
Parahippocampal	−9.4E − 3	0.421	−9.4E − 2	0.500	−3.4E − 2	6.0E − 7	−3.4E − 2	2.9E − 6

ANCOVA models tested the effect of diagnosis on ODI, controlling for age, sex, and with and without cortical thickness; bold indicates P_FDR < 0.05; CT = cortical thickness; AD = Alzheimer’s disease dementia group.