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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: Birth Defects Res. 2019 Oct 9;111(19):1577–1583. doi: 10.1002/bdr2.1597

TABLE 1.

Imaging and neurologic studies findings in three infants with congenital Zika syndrome, arthrogryposis, and diaphragmatic paralysis—Recife, Brazil

Evaluation Infant 1 (7 months) Infant 2 (19 months) Infant 3 (19 months)
Brain imaging by CT scan/MRI Cortical loss, moderate ventriculomegaly, intracranial calcifications Cortical loss, mild ventriculomegaly, intracranial calcifications, brainstem hypoplasia; cortical dysplasia by MRI Cortical loss, severe ventriculomegaly, intracranial calcifications, brainstem and cerebellar hypoplasia, Dandy–Walker malformation
Chest X-ray (CXR)/diaphragm ultrasound (USG)/CT scan Paralysis of the right diaphragm by CXR and USG Paralysis of the right diaphragm by CXR and USG Paralysis of the diaphragm, bilateral; anterior more affected by CXR, USG, and CT scan
Spinal cord MRI Not done Thin cord thoracic region, ventral predominance Not done
Electromyography Moderate chronic involvement of peripheral motor neurons Moderate chronic involvement of peripheral motor neurons Moderate chronic involvement of peripheral motor neurons
Nerve conduction study—phrenic nerve compound muscle action potential Reduced on right Reduced on right Reduced bilaterally
Hip X-ray/ultrasound Bilateral hip dislocation Bilateral hip dislocation Bilateral hip dislocation
Electroencephalogram Focal discharge, almost continuous, temporal bilateral Focal discharge, frontal bilateral Focal discharge, frontal bilateral