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. 2020 May 4;21:33. doi: 10.1186/s40360-020-00402-9

Table 3.

Indole derivatives with CobA inhibition potential in all pathogens under study

Zinc Ids Ng
− 6.7*
Ab
− 8.8*
Cc
− 7.9*
Kp
− 8.4*
Ef Hp
− 7.7*
Pa
− 6.0*
Sa
− 7.4*
St
−8.2*
ZINC04899565 −8.0 −9.5 −8.7 − 9.5 # − 8.6 − 7.2 −8.4 −9.2
ZINC49171024 −7.3 −9.1 −9.2 − 9.2 # −8.4 − 6.9 − 8.1 −9.2

*Binding energy of native ligand

# B. E not calculated due to unavailability of valid 3D structure.