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. 2020 May 1;34(9-10):701–714. doi: 10.1101/gad.335281.119

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© 2020 Beebe et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 4. — dERR mutants display reduced glycolytic oxidation. GC/MS metabolomic profiling of 6-d-old controls (blue) and dERR mutants (red) raised to adulthood on a normal diet (9% sugar) and transferred to a 15% sugar diet at eclosion. n = 8–12 independent samples with 20 animals per sample. Metabolite data are from three independent GC/MS experiments, with the exception of the fatty acid measurements, which were performed in one GC/MS experiment. Values were normalized to control levels for each metabolite. (***) P ≤ 0.001; (**) P ≤ 0.01; (ns) P > 0.05.