Figure 5. P2RY1 neurons mediate responses to laryngeal water and acid challenge.
(A) Cartoon (top) of DT-mediated ablation of Cre-expressing cells. DTR immunostaining of NJP ganglia from P2ry1-ires-Cre; loxP-DTR mice 3 weeks after intraganglionic saline (left) or DT (right) injection, far-red fluorescent Nissl counterstain (gray), scale bars: 100 μm. (B) Swallows over 20 second perfusion or 10 mechanical trials in mice indicated, n=4–9 mice, mean ± sem, *p<0.05, **p<0.005, ****p<0.00005. See also Figure S5.