Figure 5.

Models of collateral artery formation in mouse heart. Schematic figure showing three models for collateral artery formation in mouse heart: arterialization, arteriogenesis, and artery reassembly. Arterialization is the process of remodeling of capillary vessels into new collateral arteries to compensate the blood supply downstream of the obstruction. Arteriogenesis indicates small arterioles enlarge to form larger functional collateral arteries. Artery reassembly is the process that arterial endothelial cells (ECs) migrate away from arteries along existing capillaries and reassemble into collateral arteries.