A. Diagram of the fecal slurry peritonitis model. B. Core temperature. Fecal slurry was collected from WT, TLR7−/−, and TLR2−/− mice and injected i.p. to WT mice. Control mice received i.p. injection of 5% dextrose in water (D5). Twenty-four hours later, rectal temperature was measured. C. EXTEM assay. Blood was collected for E-MCF assay. ΔP = 0.05, *P < 0.05, **P < 0.01, ***P < 0.001.