| Methods |
Case‐control
Retrospective
Cross‐sectional. |
| Participants |
491 patients (304 men, 187 women). Patients included rectal cancer survivors
with permanent ostomies (termed "cases", 246 patients) and those who had similar rectal cancer
treatment‐related procedures but who had an anastomosis (termed "controls", 245 patients).
Presurvey matching was conducted by age (within 5 years), sex, and time interval since diagnosis (5‐year intervals). Patients who had their ostomy reversed were excluded from this study.
USA. |
| Interventions |
Quality of life assessment with SF‐36v2 and mCOH‐QoL‐
Ostomy |
| Outcomes |
Quality of life |
| Notes |
Evidence level: 3B.
Not stated: Tumour grade; Tumour and anastomotic distance from anal verge; pouch |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
High risk |
Retrospective, cross‐sectional case‐control study. APE patients surviving five years after their diagnosis and meeting inclusion criteria, were matched with patients, who had similar rectal cancer related treatment but with anastomosis. |
| Blinding (performance bias and detection bias)
Anterior resection or abdominoperineal resection |
High risk |
Blinding not possible due to surgical therapy. |
| Incomplete outcome data (attrition bias)
Quality of life |
Low risk |
All included patients completed the study. |
| Selective reporting (reporting bias) |
Low risk |
All QoL data reported. |
