| Methods |
Cohort
Prospective
Longidudinal. |
| Participants |
135 rectal cancer patients (64 AR) recruited from a multicenter chemotherapy study after initial Ro resection.
United Kingdom. |
| Interventions |
Quality of life assessment with EORTC‐C30 |
| Outcomes |
Quality of life |
| Notes |
Evidence level: 2B.
Not stated: TNM grade; tumour and anastomotic distance fro anal verge; pouch. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
High risk |
Prospective, longitudinal cohort study. Patients were initially part of a RCT comparing different chemotherapy regiments for colorectal cancer patients. Patients with rectal cancer were enrolled in this study. Not all eligible patients entered the study. |
| Blinding (performance bias and detection bias)
Anterior resection or abdominoperineal resection |
High risk |
Blinding not possible due to surgical therapy. |
| Incomplete outcome data (attrition bias)
Quality of life |
Low risk |
All included patients completed the study. |
| Selective reporting (reporting bias) |
Low risk |
All QoL data reported. Though some data only presented in figures. |
