Table 1. CI values for the synergistic effect of AEW541 and chemotherapeutic drugs.

Cells	Drug	Drug Dose (uM × 10)	Dose AEW(uM)	Effect	Cl	Synergism
		0.5		0.59	0.24	Strong
	rinotecan	1.0	1.5	0.71	0.17	Strong
		5.0		0.83	0.31	Synergism
		0.5		0.92	0.01	Very strong
	Gemcitabine	1.0		0.95	0.00	Very strong
		10.0		0.93	0.04	Very strong
		0.1		0.67	0.56	Synergism
	Taxol	0.5		0.85	0.40	Synergism
MCF7		1.0		0.85	0.77	Moderate
		5.0		0.75	0.37	Synergism
	Cisplatin	10.0	2.0	0.83	0.26	Strong
		20.0		0.85	0.36	Synergism
		0.5		0.71	0.29	Strong
	VP-16	1.0		0.78	0.14	Strong
		10.0		0.85	0.06	Very strong
		0.1		0.73	0.18	Strong
	Doxorubicin	1.0		0.81	0.14	Strong
		2.0		0.83	0.16	Strong

Values under Effect (fifth column) denote the proportion of cells that were killed by the combination treatment.