AML, acute myeloid leukaemia; CR, complete remission; CRc, composite complete remission; CRh, CR with incomplete haematological recovery; CRi, complete remission with incomplete neutrophil or platelet recovery; EFS, event-free survival; HMA, hypomethylating agent; ITD, internal tandem duplication; MDS, myelodysplastic syndrome; OS, overall survival; ORR, overall response rate; R/R, relapsed and/or refractory.