Khan 2014.
Study characteristics | ||
Methods | RCT. Parallel design. Location: single centre in Russia. Duration: 10 'procedures' (not clear how many procedures per day). |
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Participants | 30 children aged 5 ‐ 17 years. | |
Interventions | HFCWO versus control (control not mentioned so alternative ACT unknown, assumed that 15 participants were randomised to each treatment group). | |
Outcomes | FEV1, FVC, exercise tolerance, sputum volume and SpO₂ But as we are unaware of the alternative "control" ACT we cannot include the data in the meta‐analysis. |
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Notes | Only abstract in English, therefore translation required but even following translation the paper had limited quality and limited information as to the actual interventions and their frequency. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Stratified randomisation declared, not described. |
Allocation concealment (selection bias) | Unclear risk | Not mentioned. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not mentioned. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No drop outs. All 30 data sets included in their analysis |
Selective reporting (reporting bias) | Unclear risk | No objective data on sputum volume, although it was stated there was an improvement following the intervention. |
Other bias | Unclear risk | Not clear as abstract only in English and no clear evidence of excluded bias in translated paper. |