Table 3:
Effect of storage duration on hemoglobin increments after RBC transfusion
| Storage Duration |
Number of RBC units |
No Adjustment | Adjustment for age, sex, and BMI |
Adjustment for pre-TX Hb* |
|---|---|---|---|---|
| Estimated mean hemoglobin increment (95% CI) | ||||
| <21 days | 9,363 | 0.79 (0.77, 0.81) | 0.88 (0.86, 0.90) | 1.05 (1.02, 1.07) |
| 22–28 | 11,245 | 0.81 (0.79, 0.83) | 0.89 (0.87, 0.91) | 1.04 (1.01, 1.05) |
| 29–35 | 7,876 | 0.86 (0.84, 0.88) | 0.92 (0.90, 0.94) | 1.04 (1.01, 1.06) |
| 36–42 | 7,063 | 0.91 (0.89, 0.94) | 0.94 (0.92, 0.96) | 1.00 (0.98, 1.02) |
RBC=red blood cell; BMI=body mass index; TX=transfusion; Hb=hemoglobin
p-value <0.02 for mean estimated hemoglobin increment of >35-day stored RBCs vs. all other storage periods