Fig. 5. Assessment of different benzylic C–H substrates in oxidative cross-coupling reactions with methanol.

Isolated yields unless otherwise noted. ^{a 1}H NMR yield; isolated yield unavailable due to compound volatility. ^b See Fig. 3a for optimized conditions. ^c 15 mol % Cu/biox. ^d Reaction yield at 4 h. ^e At room temperature. ^f DCM as the solvent. ^g 20 mol % Cu/biox. ^h Only one regioisomer was observed. ⁱ At 30 °C. ^j 30 mol % Cu/biox. ^k Two regioisomers were observed with a ratio of 9:1.