Table 1.
Liver function test parameters of cases and controls
| Parameter | Case day 1 (I) | Case day 5 (II) | Case day 10 (III) | Control baseline (C) | Comparison of cases and controls | Change in cases from day 1 to 10; F (P), partial η2 |
|---|---|---|---|---|---|---|
| Total bilirubin (mg/dL) | 1.06 (0.52) | 0.62 (0.35) | 0.48 (0.25) | 0.57 (0.30) | I > C | 18.814 (<0.001)*, 0.621 |
| AST (U/L) | 109.72 (75.82) | 101.32 (59.47) | 73.56 (51.83) | 31.36 (8.11) | I, II, III > C | 10.649 (0.001)*, 0.481 |
| ALT (U/L) | 83.92 (72.98) | 96.24 (75.32) | 91.72 (61.10) | 39.44 (17.40) | I, II, III > C | 0.576 (0.570), 0.048 |
| GGT (U/L) | 348.32 (633.32) | 261.48 (472.64) | 202.88 (341.28) | 25.4 (11.28) | I, II, III > C | 2.614 (0.095), 0.185 |
| ALP (U/L) | 272.16 (106.88) | 227.64 (82.81) | 210.04 (91.59) | 228.48 (40.92) | NS | 7.083 (0.004)*, 0.381 |
| Total protein (g/dL) | 7.09 (0.72) | 7.01 (0.52) | 6.98 (0.45) | 7.56 (0.48) | I, II, III<C | 0.589 (0.563), 0.049 |
| Albumin (g/dL) | 3.98 (0.71) | 3.84 (0.52) | 3.82 (0.48) | 4.66 (0.41) | I, II, III<C | 1.519 (0.240), 0.117 |
*P<0.05, only significant differences shown in comparison of cases and controls, change in cases in LFT parameters shown in terms of Pillai’s Trace F (P value) with effect sizes. AST – Aspartate aminotransferase; ALT – Alanine aminotransferase; GGT – Gamma glutamyl transferase; ALP – Alkaline phosphatase; NS – Not significant; LFT – Liver function test