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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Neurobiol Dis. 2019 Jul 22;132:104539. doi: 10.1016/j.nbd.2019.104539

Figure 4. Behavioral assessment of juvenile motor functions.

Figure 4.

The TAF1-edited animals showed behavior deficits compared to naïve and gRNA-control group animals. The TAF1-edited showed increased beam waking time (A) and had a decreased beaming score (B) in beaming walking tests relative to naïve and gRNA-control rats. (C) Grooming was increased in the TAF1-edited rats compared to the other groups. Data are shown as mean ± S.E.M., n = 5-8 per experimental condition. *p<0.05 versus; naïve, #p<0.05 versus gRNA-control (ANOVA followed by Tukey’s test). The experiments were conducted in an investigator blinded manner.