Table 3.

Results From Primary Meta-Regression Analysis

Outcome Model	Number of Comparisons	Coefficient for Treatment Efficacy*	Standard Error	Z-Score	P
Total score	16	0.71	0.18	3.96	<0.001
Bowel symptoms	5	0.45	0.25	1.79	0.074
Systemic symptoms	5	0.41	0.25	1.64	0.101
Emotional function	5	0.32	0.25	1.29	0.196
Social function	5	0.32	0.25	1.30	0.195

^*Based on Hedges’ g effect size for treatment effects on primary efficacy variable.