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. 2008 Apr 25;93(5):543–548. doi: 10.1113/expphysiol.2007.040048

Figure 1.

Figure 1

Current view of ACE and ACE2 functions 
Angiotensin I serves as a substrate for both ACE and ACE2. Angiotensin II is known to act as a vasoconstrictor in vivo. The function of angiotensin(1–9) is not well understood. Both ACE and ACE2 are involved in the production of the vasodilator peptide angiotensin(1–7).