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. Author manuscript; available in PMC: 2020 May 4.
Published in final edited form as: Nanomedicine. 2019 Jul 23;21:102067. doi: 10.1016/j.nano.2019.102067

Figure 5.

Figure 5.

In vitro assessment of complement activation–C5a generation and phenotypic analysis of dendritic cells and macrophages. (A) Bone marrow-derived macrophages demonstrated no significant change in maturation when treated with SNAREs or DIONPs, compared to immature macrophages. (B) Bone-marrow-derived DC maturation is unaffected by the presence of DIONPS or SNAREs. (C) C5a complement fragment concentration in serum of C57BL/6j mice incubated with DIONPs, SNAREs, saline control, and zymosan positive control for 4 h at 37 °C.