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. Author manuscript; available in PMC: 2020 May 4.
Published in final edited form as: Nanomedicine. 2019 Jul 23;21:102067. doi: 10.1016/j.nano.2019.102067

Figure 6.

Figure 6.

Assessment of MAR autoantibody capture, specificity, and affinity in vitro. (A) SNAREs captured up to 2.7 μg LDH B Ab/ mg SNAREs (95% efficiency) and exhibited increased antibody entrapment at higher concentrations. (B) SNAREs reduced LDH B antibody titer in human serum by as much as 90% (patient-derived serum of mothers of children with ASD). Scrambled peptide-DIONPs and DIONPs were used as negative controls. (C) Avidity of SNAREs to MAR LDH B antibody indicating a 50% avidity index at ~3.6 M sodium thiocyanate concentration.