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. 2020 Apr 23;40(4):BSR20191764. doi: 10.1042/BSR20191764

Figure 2. ARAP1-AS1 prompted HDAC2 expression in BC by competitively binding to miR-2110.

Figure 2

(A) The sequences of wild-type and mutant ARAP1-AS1 and HDAC2 as well as that of miR-2110. (B and C) Luciferase reporter assays were conducted to confirm the interaction of miR-2110 with both ARAP1-AS1 and HDAC2 at predicted sites. (D) The interactions were validated in RISC by RIP assays. (E–H) The expression of HDAC2 in indicated cells was examined by qRT-PCR or Western blot, as appropriate. *P <0.05, **P <0.01, ***P <0.001.