Table 3. Logistic regression analysis of associations between rs4965833 polymorphism and risk of knee osteoarthritis.
| Genotype | Casesa(n=432) | Controlsa(n=523) | OR (95% CI); P | Adjusted OR (95% CI)b; P | ||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| AG vs. AA | 185/175 | 42.8/40.5 | 209/245 | 40.0/46.8 | 1.24(0.94,1.64); 0.129 | 1.24(0.94,1.64); 0.123 |
| GG vs. AA | 70/175 | 16.2/40.5 | 66/245 | 12.6/46.8 | 1.49(1.01,2.19); 0.046 | 1.49(1.01,2.20); 0.043 |
| GG+AG vs. AA | 255/175 | 59/40.5 | 275/245 | 52.6/46.8 | 1.30(1.00,1.68); 0.048 | 1.30(1.01,1.69); 0.045 |
| GG vs. AG+AA | 70/360 | 16.2/83.3 | 66/454 | 12.6/86.8 | 1.34(0.93,1.92); 0.117 | 1.34(0.93,1.93); 0.113 |
| G vs. A | 325/535 | 37.6/61.9 | 341/699 | 32.6/66.8 | 1.24(1.03,1.50); 0.023 | |
a
The genotyping was successful in 430 cases and 520 controls.
b
Adjusted for sex and age.
Bold values are statistically significant (P < 0.05).