Table 3. Haplotypes of the UCP2 polymorphisms in T1DM patients with and without DKD.

Haplotypes	T1DM controls (n = 418)	DKD cases (n = 300)	P-value
Ht 1 (-866G/Del)	0.518	0.540
Ht 2 (-866A/Del)	0.171	0.173	0.892
Ht 3 (-866G/Ins)	0.069	0.060
Ht 4 (-866A/Ins)	0.242	0.227

Data are presented as proportion. n = number of chromosomes. DKD: diabetic kidney disease; T1DM: type 1 diabetes mellitus. The first letter of the haplotypes refers to the -866G/A polymorphism and the second to the Ins/Del polymorphism. P-values for the comparisons of haplotype frequencies between patients with or with DKD were calculated using permutations tests.