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. 2020 Apr 23;40(4):BSR20193767. doi: 10.1042/BSR20193767

Figure 6. PPARγ-target gene expression in differentiated 3T3-L1 cells with or without HODE isomers.

Figure 6

The expression levels of (A) aP2, (B) C/EBPα, (C) Lpl, (D) Adipoq, and (E) AdipoR1 were measured at 4 days after the start of 3T3-L1 differentiation. All racemic mixtures of HODEs (equal amounts of (R) and (S) forms), are indicated as black bars; 10 μM PGZ and 0.1% DMSO were used as positive control (PC, white bar) and negative control (NC, gray bar), respectively. Results are expressed as mean values relative to control ± SD (n=4 each). *P<0.05 compared with NC. 9ZE, 9-(Z,E)-HODE; 9EE, 9-(E,E)-HODE; 10ZE, 10-(Z,E)-HODE; 12ZE, 12-(Z,E)-HODE; 13ZE, 13-(Z,E)-HODE; 13EE, 13-(E,E)-HODE.