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. 2020 Apr 27;53:e20200016. doi: 10.1590/0037-8682-0016-2020

TABLE 3: Histopathological results.

Histopathological findings Group 1 Group 2 Group 3 Group 4
Control Sepsis Sepsis + cefazolin Sepsis + cefazolin + etanercept
(n = 7) (n = 7) (n = 7) (n = 7)
Tubular necrosis 0 2.71 ± 0.48a 2.14 ± 0.37a,b 1 ± 0a,b,c
Tubular atrophy 0 2.85 ± 0.37a 2 ± 0a,b 1 ± 0a,b,c
Regenerative atypia 0 0 0 0
Hydropic degeneration 0 3 ± 0 2 ± 0 1 ± 0
Interstitial fibrosis 0 0 0 0
Loss of brush border 0 2.85 ± 0.37a 2.14 ± 0.37a,b 0.14 ± 0.37b,c

ap < 0.05 in comparison with control group. bp < 0.05 in comparison with sepsis group. cp < 0.05 in comparison with sepsis + cefazolin group.