TABLE 3: Histopathological results.
Histopathological findings | Group 1 | Group 2 | Group 3 | Group 4 |
---|---|---|---|---|
Control | Sepsis | Sepsis + cefazolin | Sepsis + cefazolin + etanercept | |
(n = 7) | (n = 7) | (n = 7) | (n = 7) | |
Tubular necrosis | 0 | 2.71 ± 0.48a | 2.14 ± 0.37a,b | 1 ± 0a,b,c |
Tubular atrophy | 0 | 2.85 ± 0.37a | 2 ± 0a,b | 1 ± 0a,b,c |
Regenerative atypia | 0 | 0 | 0 | 0 |
Hydropic degeneration | 0 | 3 ± 0 | 2 ± 0 | 1 ± 0 |
Interstitial fibrosis | 0 | 0 | 0 | 0 |
Loss of brush border | 0 | 2.85 ± 0.37a | 2.14 ± 0.37a,b | 0.14 ± 0.37b,c |
ap < 0.05 in comparison with control group. bp < 0.05 in comparison with sepsis group. cp < 0.05 in comparison with sepsis + cefazolin group.