. 2020 May 4;2(6):e358–e367. doi: 10.1016/S2665-9913(20)30096-5

Table 2.

Pharmacokinetic comparison of single dose intravenous and subcutaneous anakinra in healthy volunteers^*

	Intravenous (100 mg)^†	Subcutaneous (100 mg)^†
Healthy volunteers	7	8
Cmax (ng/mL)	32 193	1326
Tmax (h)	Not applicable	4·3
t_1/2(h)	1·69	3·63
AUC (ng^*hour/mL)	14 658	13 266
CL (mL/min)	122	134

Data are presented as mean values. Cmax= maximum plasma concentration. Tmax=time at which Cmax occurred. t_1/2=terminal half-life. AUC=area under plasma concentration-time curve from time 0 to infinity. CL=plasma clearance.

Adapted from Yang and et al.⁵⁶

^†

These data represent volunteers with a body-mass index <35 and a body weight ≤90 kg.