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. 2020 Mar 9;215(1):143–171. doi: 10.1534/genetics.120.303137

Table 2. Summary of parameters for experiments involving the generalized mammalian model.

Experiment Sample sizes Mutation (μ) [θ] and recombination (r) [ρ] rates Sequence length; window size Split time (τ, generations) [coalescent units] Selection coefficient (s) [σ] and time (t, generations) [coalescent units] Other parameters Figures
Generalized mammalian model, including star tree and nonsimultaneous sweeps (K{2,3,4,5}) 100 per population μ=2.5×108 [103], r=108 (uniform across replicates) [ρ=4×104] 100; 40 τ{250,500,750,1000} [τ/(2Ne){0.0125, 0.025, 0.0375, 0.05}]; τ=1000 for K=2 and star tree (K=4), and sequential starting from τ=1000 otherwise s=0.1 [σ=4000]; t[200,4000] [t/(2Ne)[0.01,0.2]] Population splits separated by 250 generations for K>2 scenarios; K>2 trees are asymmetric S1; S4; S9 and Supplemental note SN1–SN3; SN5; SN6, SN7
Admixture, distant donor (K=2) Same as above Same as above Same as above τ=1000 [τ/(2Ne)=0.05] between sampled sisters s same as above; t=1400 [t/(2Ne)=0.07] for ancestral sweeps, and t=600 [t/(2Ne)=0.03] for convergent and divergent sweeps Distant donor split from sampled populations τ=20000 generations [t/(2Ne)=1] ago; admixture occurred 200 generations [0.01 coalescent units] ago; admixture proportion α{0.05,0.1,,0.4} 4; S19
Admixture, intersister (K=2) Same as above Same as above Same as above Same as above Same as above Adaptive mutation originates in donor population and may be adaptive or not in its target sister; timing and proportion of admixture same as above Supplemental note SN4
Uneven sample sizes (K=2) Pooled sample size is 200 diploids; smaller sample size is nsmall{20,40,60} Same as above Same as above Same as above s and t same as generalized mammalian model Protocol identical to unmodified generalized mammalian model S20–S22

We provide diploid sample sizes, per-site per-generation mutation and recombination rates, and sequence length in kilobases. Additionally, we indicate the population-scaled values for mutation and recombination rates in brackets upon their first appearance, scaling by 4Ne where Ne=104 (θ=4Neμ; ρ=4Ner; σ=4Nes). The relationship between generations and coalescent units is 2Ne generations per coalescent unit.