Table 2. Summary of parameters for experiments involving the generalized mammalian model.
Experiment | Sample sizes | Mutation (μ) [θ] and recombination (r) [ρ] rates | Sequence length; window size | Split time (τ, generations) [coalescent units] | Selection coefficient (s) [σ] and time (t, generations) [coalescent units] | Other parameters | Figures |
---|---|---|---|---|---|---|---|
Generalized mammalian model, including star tree and nonsimultaneous sweeps () | 100 per population | [], (uniform across replicates) [] | 100; 40 | ,500,750, [, 0.025, 0.0375, ]; for and star tree (), and sequential starting from otherwise | []; [] | Population splits separated by 250 generations for scenarios; trees are asymmetric | S1; S4; S9 and Supplemental note SN1–SN3; SN5; SN6, SN7 |
Admixture, distant donor () | Same as above | Same as above | Same as above | [] between sampled sisters | s same as above; [] for ancestral sweeps, and [] for convergent and divergent sweeps | Distant donor split from sampled populations generations [] ago; admixture occurred 200 generations [0.01 coalescent units] ago; admixture proportion | 4; S19 |
Admixture, intersister () | Same as above | Same as above | Same as above | Same as above | Same as above | Adaptive mutation originates in donor population and may be adaptive or not in its target sister; timing and proportion of admixture same as above | Supplemental note SN4 |
Uneven sample sizes () | Pooled sample size is 200 diploids; smaller sample size is | Same as above | Same as above | Same as above | s and t same as generalized mammalian model | Protocol identical to unmodified generalized mammalian model | S20–S22 |
We provide diploid sample sizes, per-site per-generation mutation and recombination rates, and sequence length in kilobases. Additionally, we indicate the population-scaled values for mutation and recombination rates in brackets upon their first appearance, scaling by where (; ; ). The relationship between generations and coalescent units is generations per coalescent unit.