TABLE 3.
Baseline FA and FA ratio values by genotype1
| FA or FA ratio rs174537 genotype | Baseline | ||
|---|---|---|---|
| Mean | 95% CI | P value | |
| LA | |||
| GG | 35.13 | 33.79, 36.50 | 0.76 |
| GT | 35.34 | 34.40, 36.29 | |
| TT | 35.55 | 33.68, 37.46 | |
| GLA | |||
| GG | 0.42 | 0.35, 0.50 | 0.0002 |
| GT | 0.30 | 0.26, 0.33 | |
| TT | 0.21 | 0.16, 0.27 | |
| DGLA | |||
| GG | 1.44 | 1.30, 1.59 | 0.07 |
| GT | 1.58 | 1.47, 1.69 | |
| TT | 1.73 | 1.51, 1.98 | |
| ARA | |||
| GG | 8.13 | 7.48, 8.83 | 1.59 × 10−5 |
| GT | 6.63 | 6.25, 7.02 | |
| TT | 5.39 | 4.78, 6.07 | |
| EPA | |||
| GG | 0.48 | 0.40, 0.57 | 0.0024 |
| GT | 0.36 | 0.32, 0.41 | |
| TT | 0.28 | 0.22, 0.35 | |
| DPA | |||
| GG | 0.41 | 0.36, 0.47 | 0.07 |
| GT | 0.36 | 0.33, 0.40 | |
| TT | 0.32 | 0.26, 0.38 | |
| DHA | |||
| GG | 1.29 | 1.13, 1.48 | 0.99 |
| GT | 1.29 | 1.18, 1.42 | |
| TT | 1.29 | 1.07, 1.56 | |
| GLA/LA | |||
| GG | 0.012 | 0.010, 0.014 | 4.09 × 10−5 |
| GT | 0.008 | 0.007, 0.010 | |
| TT | 0.006 | 0.005, 0.008 | |
| DGLA/GLA | |||
| GG | 3.46 | 2.98, 4.01 | 7.74 × 10−11 |
| GT | 5.33 | 4.81, 5.90 | |
| TT | 8.21 | 6.69, 10.08 | |
| ARA/DGLA | |||
| GG | 5.67 | 5.02, 6.39 | 1.76 × 10−11 |
| GT | 4.20 | 3.86, 4.56 | |
| TT | 3.11 | 2.63, 3.67 | |
1
Baseline means and 95% CIs for key FAs and FA ratios. The baseline data for both oil consumption periods (visit 2 and visit 5) was used since the washout period was successful (Supplemental Table 1). FA values are presented as percentage of total FAs. The P values are from tests of whether that FA or ratio differed by genotype. ARA, arachidonic acid; DGLA, dihomo-ɣ-linolenic acid; DPA, docosapentaenoic acid; FA, fatty acid; GLA, ɣ-linolenic acid; LA, linoleic acid.