Table 3:
Association of weight change with hypertensive disorders of pregnancy, with sample limited to women with term deliveries
| Variable | Hypertensive disorder of pregnancy (N = 1,348) | No Hypertensive disorder of pregnancy (N = 6,326) | P valuea | Unadjusted incidence rate ratio | 95 % confidence interval | Adjusted incidence rate ratiob | 95% confidence interval |
|---|---|---|---|---|---|---|---|
| Early weight change (IOM category): | 0.05 | ||||||
| Inadequate | 365 (27.1) | 1,902 (30.1) | 0.93 | 0.80 – 1.08 | 0.88 | 0.75 – 1.03 | |
| Adequate | 314 (23.3) | 1,491 (23.6) | (ref) | (ref) | |||
| Excessive | 669 (49.6) | 2,933 (46.4) | 1.07 | 0.93 – 1.22 | 0.91 | 0.79 – 1.05 | |
| Mid weight change (IOM category): | < 0.001 | ||||||
| Inadequate | 489 (36.3) | 2,621 (41.4) | 1.01 | 0.86 – 1.19 | 1.00 | 0.85 – 1.18 | |
| Adequate | 218 (16.2) | 1,183 (18.7) | (ref) | (ref) | |||
| Excessive | 641 (47.6) | 2,522 (39.9) | 1.30 | 1.12 – 1.52 | 1.17 | 1.00 – 1.37 | |
| Late weight change (IOM category): | < 0.001 | ||||||
| Inadequate | 148 (11.0) | 1,018 (16.1) | 0.89 | 0.71 – 1.12 | 0.76 | 0.60 – 0.96 | |
| Adequate | 151 (11.2) | 907 (14.3) | (ref) | (ref) | |||
| Excessive | 1,049 (77.8) | 4,401 (69.6) | 1.35 | 1.14 – 1.60 | 1.19 | 1.01 – 1.42 |
a
P value for t tests for continuous variables, chi square tests for categorical variables.
b
In addition to the factors listed here, multivariable models also adjusted for maternal BMI at first visit, maternal age at first visit, maternal race, maternal education, insurance status, gravidity, smoking within 3 months of pregnancy, and maternal diabetes, all of which were significant at the p < 0.10 level with either weight gain or hypertensive disorders in bivariable analyses, but not in multivariable analyses. These incidence rate ratios also account for fixed effects by study site and subsite.