Table 3.

Table 3 shows multivariate models of time to NK cell receptor acquisition, adjusted for log ₁₀ CD34 cell count in the infused graft. The hazard ratio in this analysis indicates the risk of failure of normalization of NK cell count or NK cell receptor expression as listed in the table, based on the covariate KIR mismatch and adjusted for CD34 count in the graft. Data were adjusted for the number of stem cells infused (CD34 count) because our data showed that CD34 count significantly influenced the tempo of immune reconstitution. Infused CD3 count was also tested in this model but did not influence outcomes so was not retained in the model. Time dependence in this analysis refers to time to normalization of NK cell count or NK receptor expression after transplant, using levels measured at timepoints of 1, 3, 6 and 12 months after transplant.

Receptor	Impact of Ligand match vs. mismatch on receptor acquisition
	HR	95% CI	P-value
KIR2DL1*	0		<0.001
KIR2DL2/3*	0		<0.001
NKG2A*	1.177	0.11 – 13.04	0.894
NKG2D	2.285	1.00 – 5.23	0.050
NKp46	2.754	1.17 – 6.49	0.021
NKp44	1.866	0.41 – 8.5	0.420
2B4	2.845	1.11 – 7.31	0.030
DNAM	2.082	0.79 – 5.46	0.136

^*positive for single inhibitory receptor and negative for all other MHC inhibitory receptors.