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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Acta Biomater. 2020 Mar 13;108:142–152. doi: 10.1016/j.actbio.2020.03.014

Figure 3. Fibrin structure and gelation kinetics in alginate are dependent upon thrombin concentration.

Figure 3.

(A) Schematic and representative images of fibrin structure investigated using light reflection microscopy with varying thrombin concentrations. Green arrows indicate the presence of open pockets within the IPN. (B) Optical density of fibrin and FA IPNs at 550 nm (n=4–5). (C) Storage modulus of alginate constructs with varying CaCl2 concentrations and crosslinking times. (D) Wet weight normalized to dry weight of constructs cultured over 10 days (n=5). Different letters denote statistical significance (p<0.05).