Figure 5:
NCM song-evoked testosterone fluctuations during steroidogenesis blockade. (A) When E2 and/or testosterone syntheses are pharmacologically inhibited (light gray area, 2.5 hours duration, from 1.5 to 3.5 hours), acoustic playback (dark gray area; 30 minutes duration centered on 2.5 hours) induces differential changes in testosterone levels within NCM. Testosterone (Mean ± SEM) rises during playback only in the left NCM and only when E2 synthesis alone is blocked, whereas no such change occurs in the right hemisphere nor when the upstream testosterone synthesis is blocked in either hemisphere. * p < 0.05. (B) Schematic view of trilostane and fadrozole actions on the steroidogenesis pathway and their effects on left vs. right NCM testosterone levels during song playback.