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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Curr Opin Neurobiol. 2020 Feb 21;61:65–72. doi: 10.1016/j.conb.2020.01.012

Figure 2. Two cellular layers of transposable element control.

Figure 2.

Under normal conditions in somatic cells, many transposable elements are transcriptionally silenced by heterochromatin. Post-transcriptionally, retrotransposons are subject to nuclear and cytoplasmic degradation by piRNAs and siRNAs, respectively.