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Proposed Clinical Algorithm for Nuclear Imaging Investigations in Cases of PPGL (10)
| Condition | First choice | Second choice |
| Pheochromocytoma (apparently sporadic) | 18F-FDOPA or 123I-MIBG | 68Ga-SSA |
| Inherited pheochromocytoma (except SDHx): NF1/RET/VHL/MAX | 18F-FDOPA | 123I-MIBG or 68Ga-SSA |
| HNPGL | 68Ga-SSA | 18F-FDOPA |
| Extraadrenal sympathetic or multifocality or metastatic disease or SDHx mutation | 68Ga-SSA | 18F-FDG and 18F-FDOPA |
MIBG = metaiodobenzylguanidine; SSA = somatostatin analog.
