TABLE 2.
Patient-Based Diagnostic Accuracy of Cross-Sectional Imaging and 18F-rhPSMA-7 PET Compared with Histologic Findings for Lymph Node Metastasis
| Morphology* |
18F-rhPSMA7-PET† |
|||||
| Grade | Histology |
Histology |
||||
| Grade | Positive | Negative | Grade | Positive | Negative | |
| 1 | 4 | 1 | 1 | 13 | 1 | |
| 2 | 0 | 0 | 2 | 0 | 2 | |
| 3 | 5 | 10 | 3 | 1 | 5 | |
| 4 | 4 | 11 | 4 | 1 | 5 | |
| 5 | 5 | 18 | 5 | 3 | 27 | |
| Total | 18 | 40 | Total | 18 | 40 | |
*
Grades 1–3 are positive (positive predictive value, 72.5%) and grades 4 and 5 negative (negative predictive value, 76.3%) for LN metastasis based on highest Youden index. Sensitivity is 50.0%, specificity is 72.5%, and accuracy is 65.5%.
†
Grades 1 and 2 are positive (positive predictive value, 81.3%) and grades 3–5 negative (negative predictive value, 88.1%) for LN metastasis based on highest Youden index. Sensitivity is 72.2%, specificity is 92.5%, and accuracy is 86.2%.