TABLE 3.
Template-Based Diagnostic Accuracy of Cross-Sectional Imaging and 18F-rhPSMA-7 PET Compared with Histologic Findings for Lymph Node Metastasis
| Morphology* |
18F-rhPSMA7-PET† |
||||
| Histology |
Histology |
||||
| Grade | Positive | Negative | Grade | Positive | Negative |
| 1 | 1 | 4 | 1 | 24 | 5 |
| 2 | 0 | 0 | 2 | 4 | 5 |
| 3 | 4 | 12 | 3 | 1 | 10 |
| 4 | 11 | 25 | 4 | 2 | 17 |
| 5 | 36 | 282 | 5 | 21 | 286 |
| Total | 52 | 323 | Total | 52 | 323 |
*
Grades 1–3 are positive (positive predictive value, 28.8%) and grades 4 and 5 negative (negative predictive value, 86.7%) for LN metastasis based on highest Youden index. Sensitivity is 9.6%, specificity is 95.0%, and accuracy is 83.2%.
†
Grades 1 and 2 are positive (positive predictive value, 73.7%) and grades 3–5 negative (negative predictive value, 92.9%) for LN metastasis based on highest Youden index. Sensitivity is 53.8%, specificity is 96.9%, and accuracy is 90.9%.